“Historical trauma (HT) is cumulative emotional and psychological wounding over the lifespan and across generations, emanating from massive group trauma experiences; the historical trauma response (HTR) is the constellation of features in reaction to this trauma. The HTR often includes depression, self-destructive behavior, suicidal thoughts and gestures, anxiety, low self-esteem, anger, and difficulty recognizing and expressing emotions.”

The historical trauma response among natives and its relationship with substance abuse: a Lakota illustration. – PubMed – NCBI
http://jhavelikes.tumblr.com/post/173006703610

““We come into the world having only recently been fish and reptiles and even plants—in our youngest state, we look something like fiddlehead ferns. I think the animal, the world of nature, is essential to our capacity to live, not only imaginatively and happily in the world, but as full human beings.””

The Burden of Strangeness: Rikki Ducornet
http://jhavelikes.tumblr.com/post/172966059350

“light-dependent magnetic compass of birds provides orientation information about the spatial alignment of the geomagnetic field. It is proposed to be located in the avian retina, and be mediated by a light-induced, biochemical radical-pair mechanism involving cryptochromes as putative receptor molecules. At the same time, cryptochromes are known for their role in the negative feedback loop in the circadian clock. We measured gene expression of Cry1, Cry2 and Cry4 in the retina, muscle and brain of zebra finches over the circadian day to assess whether they showed any circadian rhythmicity. We hypothesized that retinal cryptochromes involved in magnetoreception should be expressed at a constant level over the circadian day, because birds use a light-dependent magnetic compass for orientation not only during migration, but also for spatial orientation tasks in their daily life. Cryptochromes serving in circadian tasks, on the other hand, are expected to be expressed in a rhythmic (circadian) pattern. Cry1 and Cry2 displayed a daily variation in the retina as expected for circadian clock genes, while Cry4 expressed at constant levels over time. We conclude that Cry4 is the most likely candidate magnetoreceptor of the light-dependent magnetic compass in birds.”

Expression patterns of cryptochrome genes in avian retina suggest involvement of Cry4 in light-dependent magnetoreception | Journal of The Royal Society Interface
http://jhavelikes.tumblr.com/post/172957603495

“the loss or gain of transcription factor programs that govern embryonic cell-fate specification is associated with a form of tumor plasticity characterized by the acquisition of alternative cell fates normally characteristic of adjacent organs. In human non-small cell lung cancers, downregulation of the lung lineage-specifying TF NKX2-1 is associated with tumors bearing features of various gut tissues.”

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity: Developmental Cell
http://jhavelikes.tumblr.com/post/172933090795

“Researchers recently spotted a miniature stomach, duodenum, and small intestine hidden among the cells of lung tumor samples.”

Scientists discover a tiny stomach hidden inside lung tumours, because cancer is changing
http://jhavelikes.tumblr.com/post/172932997930