about 44 per cent of the animals were slated for experiments involving “minor stress or pain for a short duration” from exposure to “non-lethal levels of drugs or chemicals.”

Nearly 26 per cent were involved in research with “moderate to severe distress or discomfort,” from exposure to drugs or chemicals “at levels that impair physiological systems.”

Slightly more than 2 per cent were in the highest category of invasiveness, involving procedures that cause “severe pain near, at, or above the pain tolerance threshold of unanesthetized conscious animals.” This includes exposure to drugs or chemicals that may cause “death, severe pain or extreme distress.”

Given a stay of execution, three lab monkeys face a new experiment: Normal life – The Globe and Mail

“There are 6,412 non-human primates deployed in research across the country, housed inside university medical schools and pharmaceutical laboratories. They are used to test new vaccines and drugs for efficacy and toxicity – a requirement under federal health regulations – or to better understand human diseases and neurological conditions, because a macaque’s biology is so similar to our own.”

Given a stay of execution, three lab monkeys face a new experiment: Normal life – The Globe and Mail

“a prisoner’s room is their own space. And with in-room internet (with obvious restrictions) and a mobile phone, some prisoners, like teenagers, spend a lot of time in there. Prisoners have their own room keys but they leave their doors unlocked, pretty much at all times.”

I deliberately sent myself to prison in Iceland – they didn’t even lock the cell doors there

“a relatively small but broad activity dataset is sufficient to train algorithms for functional prediction over the entire glycosyltransferase superfamil”

Functional and informatics analysis enables glycosyltransferase activity prediction | Nature Chemical Biology

“aging-associated insulin resistance may be mediated by changes in the gut microbiome. Age-induced gut permeability, which the authors tied to a reduction in intestinal butyrate and subsequent loss of Akkermansia muciniphila, led to increased leakage of proinflammatory factors”

Commensal bacteria contribute to insulin resistance in aging by activating innate B1a cells | Science Translational Medicine