“Organisms that thrive at cold temperatures produce ice-binding proteins to manage the nucleation and growth of ice. Bacterial ice-nucleating proteins (INP) are typically large and form aggregates in the cell membrane, while insect hyperactive antifreeze proteins (AFP) are soluble and generally small.”

How Do Size and Aggregation of Ice-binding Proteins Control their Ice Nucleation Efficiency – Journal of the American Chemical Society (ACS Publications)
http://jhavelikes.tumblr.com/post/184176965125

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